Clinical manifestations. The disease is usually manifested by diarrhea with previous or concomitant vomiting and a slight rise in temperature. In severe cases, can be significant dehydration and acidosis. Infection may also be accompanied by respiratory symptoms such as cough and runny nose.
Etiology. Rotavirus (RV) belong to the family Reoviridae, contain RNA classified as at least 5 specific antigenic groups (A to E). Group A viruses are the leading cause of diarrhea in infants, have 2 subgroups, and at least four serotypes, which were filed in person. There are reports of great gastroenteritis outbreaks in children and adults in China caused by viruses of group B. epidemiological and clinical significance of other groups of rotaviruses is definitely not installed.
The most frequently OPN in infectious diseases is determined by prerenal causes. Significant abnormalities (bypass surgery), renal blood flow as a result of centralization of blood volume depletion or loss of fluid, that is, for various shock conditions. Acute circulatory failure leads to a spasm of the renal vessels. On renal blood flow have 1/4MOK. When spasms of renal vessels in renal blood flow decreased by 50-70%. This causes a decrease in glomerular filtration rate, an increase of reabsorption of the primary filtrate and delays slag. With the continuing circulatory insufficiency increasing hypoxia causes endothelial damage a ball that starts the engine and helps glomerulotrombozu. This condition is called shock kidney and is related to secondary renal insufficiency.